[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"skill:01M6DCTDGEJ2S2CVZ5AZSN2TZC":3,"skill-same:01M6DCTDGEJ2S2CVZ5AZSN2TZC":51},{"skillNo":4,"name":5,"nameZh":6,"description":7,"descriptionZh":6,"repositoryFullName":8,"ownerLogin":9,"ownerAvatarUrl":10,"ownerAccountNo":11,"ownerDisplayName":12,"repositoryNo":13,"starsCount":14,"licenseSpdxId":15,"licenseFileUrl":6,"sourceHtmlUrl":16,"categories":17,"keywords":18,"publishedAt":25,"linkOnly":26,"markdownContent":27,"markdownBody":28,"frontMatter":29,"refName":31,"commitSha":32,"skillDirectory":33,"forksCount":14,"repositoryHtmlUrl":34,"repositoryHomepageUrl":6,"ownerHtmlUrl":35,"ownerBlogUrl":6,"ownerDescription":6,"updatedAt":36,"install":37,"resources":50},"01M6DCTDGEJ2S2CVZ5AZSN2TZC","phenibut-compchem",null,"Use when planning or running phenibut computational pharmacology with Schrodinger and PyMOL, including GABA-B docking, SAR, ADMET, MD, FEP+, QM pKa, or publication figures.","Prekzursil\u002Fagent-skills-toolchain","Prekzursil","https:\u002F\u002Favatars.githubusercontent.com\u002Fu\u002F54636077?v=4","01M6DACZ1PCQHD99SCR1YXG28B","Andrei Mihai Visalon","01M6DACZ670WZF535V3WYYSS4Z",0,"MIT","https:\u002F\u002Fgithub.com\u002FPrekzursil\u002Fagent-skills-toolchain\u002Fblob\u002Fmain\u002Fplatform\u002Frouting\u002Ffixtures\u002Fhome\u002F.agents\u002Fskills\u002Fphenibut-compchem\u002FSKILL.md",[],[19,20,21,22,23,24],"phenibut compchem","planning","use","project","docking","computational","2026-11-10 10:12:30",false,"---\nname: phenibut-compchem\ndescription: \"Use when planning or running phenibut computational pharmacology with Schrodinger and PyMOL, including GABA-B docking, SAR, ADMET, MD, FEP+, QM pKa, or publication figures.\"\nmetadata:\n  type: project\n---\n\n# Phenibut Computational Pharmacology — Tool Routing & Pipeline\n\nCompanion to `proof_empty\u002FRESEARCH_PLAN.md` and `proof_empty\u002FSCHRODINGER_TOOLKIT.md`\n(the authoritative capability map + gap analysis). Read those for the full module\u002Ffeature detail.\n\n## Ground truth\n\n- **You own the full Schrodinger Drug Discovery Suite** (2026-2, licensed to 2050): Glide, IFD\u002FIFD-MD,\n  FEP+, Desmond, Jaguar\u002FQSite (QM), Prime+STA_GPCR, QikProp, Phase, SiteMap, WaterMap, Epik,\n  MacroModel, Canvas, AutoQSAR, AutoDesigner. **Buy nothing for the structural\u002Fchemistry layer.**\n- **PyMOL 3.1.7** (Incentive) is the only figure tool. Headless: `Scripts\\pymol.exe -cq script.pml`.\n  License lives at `%USERPROFILE%\\.pymol\\license.lic` (must be the real entitlement, not the\n  auto-generated eval token — else figures get a watermark).\n- **The mechanistic \"why\" questions (dopamine puzzle, withdrawal, prosocial effect) are\n  neurobiology\u002Fsystems pharmacology, not docking.** Corpus synthesis + free tools (PK-Sim,\n  STRING\u002FCytoscape, NEURON\u002FBrian2) are the main engine; computation tests falsifiable sub-hypotheses.\n\n## MCP: `schrodinger` (server at `C:\\Users\\agentuser\\source\\repos\\schrodinger-mcp\\server.py`)\n\nAfter editing the server, **reconnect the MCP \u002F restart Claude Code** to reload it.\n\nTested, ready: `schrodinger_version`, `backend_info`, `smiles_to_3d`, `molecule_properties`,\n`convert_structure`, `ligprep`, `qikprop_admet`, `glide_grid`, `glide_dock`, `prepwizard`,\n`prime_mmgbsa`, `run_schrodinger_python`, **`pdb_fetch`**, **`qikprop_parse_results`**, **`pymol_render`**.\n\n### Standard structure-based pipeline (GABA-B + analogs)\n### Still needs an external install (no MCP covers it)\n### Gotchas\n","# Phenibut Computational Pharmacology — Tool Routing & Pipeline\n\nCompanion to `proof_empty\u002FRESEARCH_PLAN.md` and `proof_empty\u002FSCHRODINGER_TOOLKIT.md`\n(the authoritative capability map + gap analysis). Read those for the full module\u002Ffeature detail.\n\n## Ground truth\n\n- **You own the full Schrodinger Drug Discovery Suite** (2026-2, licensed to 2050): Glide, IFD\u002FIFD-MD,\n  FEP+, Desmond, Jaguar\u002FQSite (QM), Prime+STA_GPCR, QikProp, Phase, SiteMap, WaterMap, Epik,\n  MacroModel, Canvas, AutoQSAR, AutoDesigner. **Buy nothing for the structural\u002Fchemistry layer.**\n- **PyMOL 3.1.7** (Incentive) is the only figure tool. Headless: `Scripts\\pymol.exe -cq script.pml`.\n  License lives at `%USERPROFILE%\\.pymol\\license.lic` (must be the real entitlement, not the\n  auto-generated eval token — else figures get a watermark).\n- **The mechanistic \"why\" questions (dopamine puzzle, withdrawal, prosocial effect) are\n  neurobiology\u002Fsystems pharmacology, not docking.** Corpus synthesis + free tools (PK-Sim,\n  STRING\u002FCytoscape, NEURON\u002FBrian2) are the main engine; computation tests falsifiable sub-hypotheses.\n\n## MCP: `schrodinger` (server at `C:\\Users\\agentuser\\source\\repos\\schrodinger-mcp\\server.py`)\n\nAfter editing the server, **reconnect the MCP \u002F restart Claude Code** to reload it.\n\nTested, ready: `schrodinger_version`, `backend_info`, `smiles_to_3d`, `molecule_properties`,\n`convert_structure`, `ligprep`, `qikprop_admet`, `glide_grid`, `glide_dock`, `prepwizard`,\n`prime_mmgbsa`, `run_schrodinger_python`, **`pdb_fetch`**, **`qikprop_parse_results`**, **`pymol_render`**.\n\n### Standard structure-based pipeline (GABA-B + analogs)\n### Still needs an external install (no MCP covers it)\n### Gotchas\n",{"name":5,"metadata":30,"description":7},{"type":22},"main","a298c929b6cbd662e1fce54302ce520d5ceea1a5","platform\u002Frouting\u002Ffixtures\u002Fhome\u002F.agents\u002Fskills\u002Fphenibut-compchem","https:\u002F\u002Fgithub.com\u002FPrekzursil\u002Fagent-skills-toolchain","https:\u002F\u002Fgithub.com\u002FPrekzursil","2026-11-02 14:30:57",{"source":8,"skillName":5,"commands":38,"prompt":48,"zipAvailable":49},[39,42,45],{"tool":40,"command":41},"npx","npx skills add Prekzursil\u002Fagent-skills-toolchain --skill phenibut-compchem",{"tool":43,"command":44},"bunx","bunx skills add Prekzursil\u002Fagent-skills-toolchain --skill phenibut-compchem",{"tool":46,"command":47},"pnpm","pnpm dlx skills add Prekzursil\u002Fagent-skills-toolchain --skill phenibut-compchem","安装技能，技能地址：https:\u002F\u002Fgithub.com\u002FPrekzursil\u002Fagent-skills-toolchain\u002Fblob\u002Fmain\u002Fplatform\u002Frouting\u002Ffixtures\u002Fhome\u002F.agents\u002Fskills\u002Fphenibut-compchem\u002FSKILL.md",true,[],[52,73,104,131,144,160],{"skillNo":53,"name":54,"nameZh":6,"description":55,"descriptionZh":6,"repositoryFullName":8,"ownerLogin":9,"ownerAvatarUrl":10,"ownerAccountNo":11,"ownerDisplayName":12,"repositoryNo":13,"starsCount":14,"licenseSpdxId":15,"licenseFileUrl":6,"sourceHtmlUrl":56,"categories":57,"keywords":58,"publishedAt":25},"01M6DF7D7478R55P46REYH4QAC","clarify-requirements","Resolve genuine pre-execution ambiguity by scanning repo context, generating 1-6 grounded options, and asking 1-3 focused questions via AskUserQuestion. NOT for mid-task use (injection risk); NOT when the goal is already unambiguous; use to disambiguate vague prompts before any file edits.","https:\u002F\u002Fgithub.com\u002FPrekzursil\u002Fagent-skills-toolchain\u002Fblob\u002Fmain\u002Ftools\u002Fworkspace-hooks\u002Fskills\u002Fclarify-requirements\u002FSKILL.md",[],[59,60,61,62,63,64,65,66,67,21,68,69,70,71,72],"clarify requirements","clarify","requirements","risk","options","task","prompts","goal","scanning","context","repo","injection","execution","file",{"skillNo":74,"name":75,"nameZh":6,"description":76,"descriptionZh":6,"repositoryFullName":8,"ownerLogin":9,"ownerAvatarUrl":10,"ownerAccountNo":11,"ownerDisplayName":12,"repositoryNo":13,"starsCount":14,"licenseSpdxId":15,"licenseFileUrl":6,"sourceHtmlUrl":77,"categories":78,"keywords":84,"publishedAt":25},"01M6DF79CA4BHJS66J8EZDBPWJ","openmm-md","Run FREE, open-source, Windows-native GPU molecular dynamics via the openmm-md MCP (OpenMM + CUDA on the local NVIDIA GPU). Use for protein \u002F protein-ligand MD when you want a free stack or are on Windows without a Schrodinger license. Covers the full workflow (prepare, solvate, minimize, equilibrate, production, analyze, mmgbsa) AND an honest decision guide vs Schrodinger Desmond, including how to run Desmond legitimately on Linux or a cloud GPU with a real license. This is a deliberately LESSER free alternative and does NOT replace the schrodinger MCP tools. Do NOT use it to pick a free tool when a validated FEP+, WaterMap, IFD-MD, or Prime MM-GBSA result is actually required.","https:\u002F\u002Fgithub.com\u002FPrekzursil\u002Fagent-skills-toolchain\u002Fblob\u002Fmain\u002Ftools\u002Fmcp\u002Fopenmm-md-mcp\u002Fskill\u002Fopenmm-md\u002FSKILL.md",[79],{"categoryNo":80,"categoryName":81,"taxonomyType":82,"taxonomyTypeDesc":83},"01JBSEEDCAT000000000000023","Skill与智能体开发","SCENARIO","使用场景",[85,86,87,88,89,90,91,92,93,94,95,96,97,98,21,99,100,101,102,103],"openmm md","how","decision","pick","linux","analyze","tool","stack","open","NVIDIA","gpu","license","workflow","windows","free","molecular dynamics","local","do","MCP",{"skillNo":105,"name":106,"nameZh":6,"description":107,"descriptionZh":6,"repositoryFullName":8,"ownerLogin":9,"ownerAvatarUrl":10,"ownerAccountNo":11,"ownerDisplayName":12,"repositoryNo":13,"starsCount":14,"licenseSpdxId":15,"licenseFileUrl":6,"sourceHtmlUrl":108,"categories":109,"keywords":116,"publishedAt":25},"01M6DF76C1MG85VEWP8VZCBNMN","visual-review","Take screenshots of web pages and UI using Playwright for visual review and iteration","https:\u002F\u002Fgithub.com\u002FPrekzursil\u002Fagent-skills-toolchain\u002Fblob\u002Fmain\u002Ftools\u002Feditor\u002Fmetaswarm\u002Fskills\u002Fvisual-review\u002FSKILL.md",[110,113],{"categoryNo":111,"categoryName":112,"taxonomyType":82,"taxonomyTypeDesc":83},"01JBSEEDCAT000000000000003","演示文稿",{"categoryNo":114,"categoryName":115,"taxonomyType":82,"taxonomyTypeDesc":83},"01JBSEEDCAT000000000000008","测试与质量",[117,118,119,120,121,122,123,124,125,126,86,127,128,129,130],"review","visual","visual review","pages","web","false","iteration","take","check","slides","ui","screenshot","playwright","screenshots",{"skillNo":132,"name":133,"nameZh":6,"description":134,"descriptionZh":6,"repositoryFullName":8,"ownerLogin":9,"ownerAvatarUrl":10,"ownerAccountNo":11,"ownerDisplayName":12,"repositoryNo":13,"starsCount":14,"licenseSpdxId":15,"licenseFileUrl":6,"sourceHtmlUrl":135,"categories":136,"keywords":137,"publishedAt":25},"01M6DF73AQVCBZKEN0YXEX9FXP","status","Diagnostic status report — shows metaswarm installation state, project setup, and potential issues","https:\u002F\u002Fgithub.com\u002FPrekzursil\u002Fagent-skills-toolchain\u002Fblob\u002Fmain\u002Ftools\u002Feditor\u002Fmetaswarm\u002Fskills\u002Fstatus\u002FSKILL.md",[],[133,138,139,22,140,141,142,143],"setup","report","installation","project setup","issues","state",{"skillNo":145,"name":146,"nameZh":6,"description":147,"descriptionZh":6,"repositoryFullName":8,"ownerLogin":9,"ownerAvatarUrl":10,"ownerAccountNo":11,"ownerDisplayName":12,"repositoryNo":13,"starsCount":14,"licenseSpdxId":15,"licenseFileUrl":6,"sourceHtmlUrl":148,"categories":149,"keywords":151,"publishedAt":25},"01M6DF6X6C2XB0P6GX76P7TTYV","start","Use when starting work on any task, when the user mentions metaswarm, or when the user wants to begin tracked development work","https:\u002F\u002Fgithub.com\u002FPrekzursil\u002Fagent-skills-toolchain\u002Fblob\u002Fmain\u002Ftools\u002Feditor\u002Fmetaswarm\u002Fskills\u002Fstart\u002FSKILL.md",[150],{"categoryNo":80,"categoryName":81,"taxonomyType":82,"taxonomyTypeDesc":83},[146,152,64,153,154,155,21,156,157,158,159],"start issue","issue","ready","work on issue","user","work","work on","development",{"skillNo":161,"name":138,"nameZh":6,"description":162,"descriptionZh":6,"repositoryFullName":8,"ownerLogin":9,"ownerAvatarUrl":10,"ownerAccountNo":11,"ownerDisplayName":12,"repositoryNo":13,"starsCount":14,"licenseSpdxId":15,"licenseFileUrl":6,"sourceHtmlUrl":163,"categories":164,"keywords":165,"publishedAt":25},"01M6DF6QMJ9AJKFKHHKRT005PQ","Interactive project setup — detects your project, configures metaswarm, writes project-local files","https:\u002F\u002Fgithub.com\u002FPrekzursil\u002Fagent-skills-toolchain\u002Fblob\u002Fmain\u002Ftools\u002Feditor\u002Fmetaswarm\u002Fskills\u002Fsetup\u002FSKILL.md",[],[138,22,101,166,141,167],"files","interactive"]