[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"skill:01M6DCGZ0B3K3B6HDVVVWRFR4P":3,"skill-same:01M6DCGZ0B3K3B6HDVVVWRFR4P":72},{"skillNo":4,"name":5,"nameZh":6,"description":7,"descriptionZh":6,"repositoryFullName":8,"ownerLogin":9,"ownerAvatarUrl":10,"ownerAccountNo":11,"ownerDisplayName":12,"repositoryNo":13,"starsCount":14,"licenseSpdxId":15,"licenseFileUrl":6,"sourceHtmlUrl":16,"categories":17,"keywords":26,"publishedAt":47,"linkOnly":48,"markdownContent":49,"markdownBody":50,"frontMatter":51,"refName":52,"commitSha":53,"skillDirectory":54,"forksCount":14,"repositoryHtmlUrl":55,"repositoryHomepageUrl":6,"ownerHtmlUrl":56,"ownerBlogUrl":6,"ownerDescription":6,"updatedAt":57,"install":58,"resources":71},"01M6DCGZ0B3K3B6HDVVVWRFR4P","ddi-admet-research",null,"Use as the front-end\u002Frouter for biomedical research via the tooluniverse MCP server (Harvard Zitnik lab, 2206 tools) - drug-drug interactions, ADMET\u002Fphyschem prediction, CYP450 enzyme roles, target research, FDA drug labels, drug repurposing, and pharmacovigilance. Routes to the detailed installed tooluniverse-* skills; covers the uvx registration. Use when a question needs biomedical knowledge-base lookups rather than local structure computation.","Prekzursil\u002Fagent-skills-toolchain","Prekzursil","https:\u002F\u002Favatars.githubusercontent.com\u002Fu\u002F54636077?v=4","01M6DACZ1PCQHD99SCR1YXG28B","Andrei Mihai Visalon","01M6DACZ670WZF535V3WYYSS4Z",0,"MIT","https:\u002F\u002Fgithub.com\u002FPrekzursil\u002Fagent-skills-toolchain\u002Fblob\u002Fmain\u002Fplatform\u002Frouting\u002Ffixtures\u002Fhome\u002F.agents\u002Fskills\u002Fddi-admet-research\u002FSKILL.md",[18,23],{"categoryNo":19,"categoryName":20,"taxonomyType":21,"taxonomyTypeDesc":22},"01JBSEEDCAT000000000000021","资料检索与研究","SCENARIO","使用场景",{"categoryNo":24,"categoryName":25,"taxonomyType":21,"taxonomyTypeDesc":22},"01JBSEEDCAT000000000000023","Skill与智能体开发",[27,28,29,30,31,32,33,34,35,36,37,38,39,40,41,42,43,44,45,46],"research","ddi admet research","registration","tooluniverse","as","end","roles","biomedical","local","structure","base","MCP","fda","router","use","question","knowledge","Tools","server","mcp server","2026-11-10 10:12:30",false,"---\nname: ddi-admet-research\ndescription: Use as the front-end\u002Frouter for biomedical research via the tooluniverse MCP server (Harvard Zitnik lab, 2206 tools) - drug-drug interactions, ADMET\u002Fphyschem prediction, CYP450 enzyme roles, target research, FDA drug labels, drug repurposing, and pharmacovigilance. Routes to the detailed installed tooluniverse-* skills; covers the uvx registration. Use when a question needs biomedical knowledge-base lookups rather than local structure computation.\n---\n\n# DDI \u002F ADMET Research (ToolUniverse front-end)\n\n## Overview\n\nThis skill is a THIN ROUTER over the `tooluniverse` MCP server and the already-installed `tooluniverse-*` deep skills. Do NOT re-implement DDI\u002FADMET reasoning here - dispatch to the specialized skill, then call ToolUniverse tools.\n\n- Server: ToolUniverse (Apache-2.0, Harvard Zitnik lab), 2206 biomedical tools covering DDI, ADMET, CYP, targets, FDA labels, repurposing, and pharmacovigilance.\n- Registration (verified, stdio): command `uvx`, args `tooluniverse==1.2.4`, env `PYTHONIOENCODING` = `utf-8`. The stdio entry point is `tooluniverse.smcp_server:run_default_stdio_server`.\n- Cross-platform: `uvx` works on Windows and POSIX identically; no path edits needed.\n\n## Route to the Right Installed Skill\n\nDeep, ready-made skills already live at `~\u002F.agents\u002Fskills` (on Windows: `C:\\Users\\agentuser\\.agents\\skills`). Pick by intent:\n\n- Drug-drug interactions, polypharmacy, CYP\u002FUGT mechanisms -> `tooluniverse-drug-drug-interaction`\n- ADMET \u002F physicochemical \u002F drug-likeness prediction -> `tooluniverse-admet-prediction`\n- Hazard, GHS, handling, exposure -> `tooluniverse-chemical-safety`\n- Target identification \u002F validation -> `tooluniverse-target-research`\n- Repositioning \u002F new indications -> `tooluniverse-drug-repurposing`\n- Adverse events, signal detection, post-market safety -> `tooluniverse-pharmacovigilance`\n- Mechanism of action -> `tooluniverse-drug-mechanism-research`\n\nInvoke the matching skill first; this front-end only handles routing + the connection.\n\n### Real ToolUniverse Tools (verified in use)\n### Quick Workflow\n### Common Mistakes\n### Related Skills\n","# DDI \u002F ADMET Research (ToolUniverse front-end)\n\n## Overview\n\nThis skill is a THIN ROUTER over the `tooluniverse` MCP server and the already-installed `tooluniverse-*` deep skills. Do NOT re-implement DDI\u002FADMET reasoning here - dispatch to the specialized skill, then call ToolUniverse tools.\n\n- Server: ToolUniverse (Apache-2.0, Harvard Zitnik lab), 2206 biomedical tools covering DDI, ADMET, CYP, targets, FDA labels, repurposing, and pharmacovigilance.\n- Registration (verified, stdio): command `uvx`, args `tooluniverse==1.2.4`, env `PYTHONIOENCODING` = `utf-8`. The stdio entry point is `tooluniverse.smcp_server:run_default_stdio_server`.\n- Cross-platform: `uvx` works on Windows and POSIX identically; no path edits needed.\n\n## Route to the Right Installed Skill\n\nDeep, ready-made skills already live at `~\u002F.agents\u002Fskills` (on Windows: `C:\\Users\\agentuser\\.agents\\skills`). Pick by intent:\n\n- Drug-drug interactions, polypharmacy, CYP\u002FUGT mechanisms -> `tooluniverse-drug-drug-interaction`\n- ADMET \u002F physicochemical \u002F drug-likeness prediction -> `tooluniverse-admet-prediction`\n- Hazard, GHS, handling, exposure -> `tooluniverse-chemical-safety`\n- Target identification \u002F validation -> `tooluniverse-target-research`\n- Repositioning \u002F new indications -> `tooluniverse-drug-repurposing`\n- Adverse events, signal detection, post-market safety -> `tooluniverse-pharmacovigilance`\n- Mechanism of action -> `tooluniverse-drug-mechanism-research`\n\nInvoke the matching skill first; this front-end only handles routing + the connection.\n\n### Real ToolUniverse Tools (verified in use)\n### Quick Workflow\n### Common Mistakes\n### Related Skills\n",{"name":5,"description":7},"main","a298c929b6cbd662e1fce54302ce520d5ceea1a5","platform\u002Frouting\u002Ffixtures\u002Fhome\u002F.agents\u002Fskills\u002Fddi-admet-research","https:\u002F\u002Fgithub.com\u002FPrekzursil\u002Fagent-skills-toolchain","https:\u002F\u002Fgithub.com\u002FPrekzursil","2026-11-02 14:30:57",{"source":8,"skillName":5,"commands":59,"prompt":69,"zipAvailable":70},[60,63,66],{"tool":61,"command":62},"npx","npx skills add Prekzursil\u002Fagent-skills-toolchain --skill ddi-admet-research",{"tool":64,"command":65},"bunx","bunx skills add Prekzursil\u002Fagent-skills-toolchain --skill ddi-admet-research",{"tool":67,"command":68},"pnpm","pnpm dlx skills add Prekzursil\u002Fagent-skills-toolchain --skill ddi-admet-research","安装技能，技能地址：https:\u002F\u002Fgithub.com\u002FPrekzursil\u002Fagent-skills-toolchain\u002Fblob\u002Fmain\u002Fplatform\u002Frouting\u002Ffixtures\u002Fhome\u002F.agents\u002Fskills\u002Fddi-admet-research\u002FSKILL.md",true,[],[73,94,119,146,160,176],{"skillNo":74,"name":75,"nameZh":6,"description":76,"descriptionZh":6,"repositoryFullName":8,"ownerLogin":9,"ownerAvatarUrl":10,"ownerAccountNo":11,"ownerDisplayName":12,"repositoryNo":13,"starsCount":14,"licenseSpdxId":15,"licenseFileUrl":6,"sourceHtmlUrl":77,"categories":78,"keywords":79,"publishedAt":47},"01M6DF7D7478R55P46REYH4QAC","clarify-requirements","Resolve genuine pre-execution ambiguity by scanning repo context, generating 1-6 grounded options, and asking 1-3 focused questions via AskUserQuestion. NOT for mid-task use (injection risk); NOT when the goal is already unambiguous; use to disambiguate vague prompts before any file edits.","https:\u002F\u002Fgithub.com\u002FPrekzursil\u002Fagent-skills-toolchain\u002Fblob\u002Fmain\u002Ftools\u002Fworkspace-hooks\u002Fskills\u002Fclarify-requirements\u002FSKILL.md",[],[80,81,82,83,84,85,86,87,88,41,89,90,91,92,93],"clarify requirements","clarify","requirements","risk","options","task","prompts","goal","scanning","context","repo","injection","execution","file",{"skillNo":95,"name":96,"nameZh":6,"description":97,"descriptionZh":6,"repositoryFullName":8,"ownerLogin":9,"ownerAvatarUrl":10,"ownerAccountNo":11,"ownerDisplayName":12,"repositoryNo":13,"starsCount":14,"licenseSpdxId":15,"licenseFileUrl":6,"sourceHtmlUrl":98,"categories":99,"keywords":101,"publishedAt":47},"01M6DF79CA4BHJS66J8EZDBPWJ","openmm-md","Run FREE, open-source, Windows-native GPU molecular dynamics via the openmm-md MCP (OpenMM + CUDA on the local NVIDIA GPU). Use for protein \u002F protein-ligand MD when you want a free stack or are on Windows without a Schrodinger license. Covers the full workflow (prepare, solvate, minimize, equilibrate, production, analyze, mmgbsa) AND an honest decision guide vs Schrodinger Desmond, including how to run Desmond legitimately on Linux or a cloud GPU with a real license. This is a deliberately LESSER free alternative and does NOT replace the schrodinger MCP tools. Do NOT use it to pick a free tool when a validated FEP+, WaterMap, IFD-MD, or Prime MM-GBSA result is actually required.","https:\u002F\u002Fgithub.com\u002FPrekzursil\u002Fagent-skills-toolchain\u002Fblob\u002Fmain\u002Ftools\u002Fmcp\u002Fopenmm-md-mcp\u002Fskill\u002Fopenmm-md\u002FSKILL.md",[100],{"categoryNo":24,"categoryName":25,"taxonomyType":21,"taxonomyTypeDesc":22},[102,103,104,105,106,107,108,109,110,111,112,113,114,115,41,116,117,35,118,38],"openmm md","how","decision","pick","linux","analyze","tool","stack","open","NVIDIA","gpu","license","workflow","windows","free","molecular dynamics","do",{"skillNo":120,"name":121,"nameZh":6,"description":122,"descriptionZh":6,"repositoryFullName":8,"ownerLogin":9,"ownerAvatarUrl":10,"ownerAccountNo":11,"ownerDisplayName":12,"repositoryNo":13,"starsCount":14,"licenseSpdxId":15,"licenseFileUrl":6,"sourceHtmlUrl":123,"categories":124,"keywords":131,"publishedAt":47},"01M6DF76C1MG85VEWP8VZCBNMN","visual-review","Take screenshots of web pages and UI using Playwright for visual review and iteration","https:\u002F\u002Fgithub.com\u002FPrekzursil\u002Fagent-skills-toolchain\u002Fblob\u002Fmain\u002Ftools\u002Feditor\u002Fmetaswarm\u002Fskills\u002Fvisual-review\u002FSKILL.md",[125,128],{"categoryNo":126,"categoryName":127,"taxonomyType":21,"taxonomyTypeDesc":22},"01JBSEEDCAT000000000000003","演示文稿",{"categoryNo":129,"categoryName":130,"taxonomyType":21,"taxonomyTypeDesc":22},"01JBSEEDCAT000000000000008","测试与质量",[132,133,134,135,136,137,138,139,140,141,103,142,143,144,145],"review","visual","visual review","pages","web","false","iteration","take","check","slides","ui","screenshot","playwright","screenshots",{"skillNo":147,"name":148,"nameZh":6,"description":149,"descriptionZh":6,"repositoryFullName":8,"ownerLogin":9,"ownerAvatarUrl":10,"ownerAccountNo":11,"ownerDisplayName":12,"repositoryNo":13,"starsCount":14,"licenseSpdxId":15,"licenseFileUrl":6,"sourceHtmlUrl":150,"categories":151,"keywords":152,"publishedAt":47},"01M6DF73AQVCBZKEN0YXEX9FXP","status","Diagnostic status report — shows metaswarm installation state, project setup, and potential issues","https:\u002F\u002Fgithub.com\u002FPrekzursil\u002Fagent-skills-toolchain\u002Fblob\u002Fmain\u002Ftools\u002Feditor\u002Fmetaswarm\u002Fskills\u002Fstatus\u002FSKILL.md",[],[148,153,154,155,156,157,158,159],"setup","report","project","installation","project setup","issues","state",{"skillNo":161,"name":162,"nameZh":6,"description":163,"descriptionZh":6,"repositoryFullName":8,"ownerLogin":9,"ownerAvatarUrl":10,"ownerAccountNo":11,"ownerDisplayName":12,"repositoryNo":13,"starsCount":14,"licenseSpdxId":15,"licenseFileUrl":6,"sourceHtmlUrl":164,"categories":165,"keywords":167,"publishedAt":47},"01M6DF6X6C2XB0P6GX76P7TTYV","start","Use when starting work on any task, when the user mentions metaswarm, or when the user wants to begin tracked development work","https:\u002F\u002Fgithub.com\u002FPrekzursil\u002Fagent-skills-toolchain\u002Fblob\u002Fmain\u002Ftools\u002Feditor\u002Fmetaswarm\u002Fskills\u002Fstart\u002FSKILL.md",[166],{"categoryNo":24,"categoryName":25,"taxonomyType":21,"taxonomyTypeDesc":22},[162,168,85,169,170,171,41,172,173,174,175],"start issue","issue","ready","work on issue","user","work","work on","development",{"skillNo":177,"name":153,"nameZh":6,"description":178,"descriptionZh":6,"repositoryFullName":8,"ownerLogin":9,"ownerAvatarUrl":10,"ownerAccountNo":11,"ownerDisplayName":12,"repositoryNo":13,"starsCount":14,"licenseSpdxId":15,"licenseFileUrl":6,"sourceHtmlUrl":179,"categories":180,"keywords":181,"publishedAt":47},"01M6DF6QMJ9AJKFKHHKRT005PQ","Interactive project setup — detects your project, configures metaswarm, writes project-local files","https:\u002F\u002Fgithub.com\u002FPrekzursil\u002Fagent-skills-toolchain\u002Fblob\u002Fmain\u002Ftools\u002Feditor\u002Fmetaswarm\u002Fskills\u002Fsetup\u002FSKILL.md",[],[153,155,35,182,157,183],"files","interactive"]