AGENT SKILL

ddi-admet-research

Use as the front-end/router for biomedical research via the tooluniverse MCP server (Harvard Zitnik lab, 2206 tools) - drug-drug interactions, ADMET/physchem prediction, CYP450 enzyme roles, target research, FDA drug labels, drug repurposing, and pharmacovigilance. Routes to the detailed installed tooluniverse-* skills; covers the uvx registration. Use when a question needs biomedical knowledge-base lookups rather than local structure computation.

License 许可
MIT
最近更新
2026-11-02
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01 前言 Front Matter

name
ddi-admet-research
description
Use as the front-end/router for biomedical research via the tooluniverse MCP server (Harvard Zitnik lab, 2206 tools) - drug-drug interactions, ADMET/physchem prediction, CYP450 enzyme roles, target research, FDA drug labels, drug repurposing, and pharmacovigilance. Routes to the detailed installed tooluniverse-* skills; covers the uvx registration. Use when a question needs biomedical knowledge-base lookups rather than local structure computation.

03 SKILL.md 正文

DDI / ADMET Research (ToolUniverse front-end)

Overview

This skill is a THIN ROUTER over the tooluniverse MCP server and the already-installed tooluniverse-* deep skills. Do NOT re-implement DDI/ADMET reasoning here - dispatch to the specialized skill, then call ToolUniverse tools.

  • Server: ToolUniverse (Apache-2.0, Harvard Zitnik lab), 2206 biomedical tools covering DDI, ADMET, CYP, targets, FDA labels, repurposing, and pharmacovigilance.
  • Registration (verified, stdio): command uvx, args tooluniverse==1.2.4, env PYTHONIOENCODING = utf-8. The stdio entry point is tooluniverse.smcp_server:run_default_stdio_server.
  • Cross-platform: uvx works on Windows and POSIX identically; no path edits needed.

Route to the Right Installed Skill

Deep, ready-made skills already live at ~/.agents/skills (on Windows: C:\Users\agentuser\.agents\skills). Pick by intent:

  • Drug-drug interactions, polypharmacy, CYP/UGT mechanisms -> tooluniverse-drug-drug-interaction
  • ADMET / physicochemical / drug-likeness prediction -> tooluniverse-admet-prediction
  • Hazard, GHS, handling, exposure -> tooluniverse-chemical-safety
  • Target identification / validation -> tooluniverse-target-research
  • Repositioning / new indications -> tooluniverse-drug-repurposing
  • Adverse events, signal detection, post-market safety -> tooluniverse-pharmacovigilance
  • Mechanism of action -> tooluniverse-drug-mechanism-research

Invoke the matching skill first; this front-end only handles routing + the connection.

Real ToolUniverse Tools (verified in use)

Quick Workflow

Common Mistakes

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